Acetaminophen intoxication
Tylenol overdose
History / PE
:
Nausea,
vomiting
, anorexia (early stage)
Treatment
:
1
) Within four hours of ingestion, administer activated charcoal
2
) Check serum levels at 4 hour mark (first data/decision point)
3
) Refer to
Rumack-Matthew normogram
(provides likelihood of hepatotoxic effects of acetaminophen OD based on plasma levels and hours after ingestion)
4
) Administer N-acteylcysteine / mucomyst as appropriate (can be administered within 8 hrs of ingestion without affecting outcome)
July 30th 2010
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Drugs
Internal Medicine
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