Anti-arrhythmic drugs

Anti-arrhythmic drugs
  • Notes:
    CLASS I A (lengthen AP)
    (Na+ channel blockers)
    Q uinidine ( Torsades de pointes , cinchonism)
    P rocainamide (lupus like syndrome)
    D isopyroamide
    A miodarone

    CLASS I B (shorten AP)
    (acute ventricular arrhythmias)
    L idocaine
    M exiletine
    O cainide
    P henytoin

    CLASS I C (no effect on AP)
    F lecainide
    E ncainide
    P ropafenone

    CLASS II (decrease CAMP, calcium channels)
    P ropranolol (wheezing)
    A tenolol
    M etoprolol
    T Imolol
    E smolol

    CLASS III (potassium channel blockers)
    B retylium
    A miodarone (PFTs, LFTs, TFTs)
    S etalol (tosade de pointes)
    I butilide

    CLASS IV (calcium channel blockers)
    *prevent nodal arrhythmias, SVT
    V erapamil (flushing, edema)
    D iltiazem



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August 6th 2010