Celiac sprue Gluten enteropathy

• Facts:
  Autoimmune malabsorption disorder of the small intestines
• History / PE:
  Dermatitis herpetiformis
  Iron deficiency anemia (iron absorbed in duodenum)
  Intermittent abdominal distension
  Flatulence
  Greasy stools
  
• Diagnosis:
  Anti-gliadin / anti-endomysium antibodies
  Effacement of small intestine villi
  Abnormal D-xylose absorption (no change after ABX)
  Iron deficiency anemia
• Treatment:
  Gluten-free diet
• Complications:
  Osteopenia, osteoporosis
• Differential Diagnosis:
  1) Bacterial overgrowth (abnormal D-xylose absorption, normalizes post abx)
  
  2) Topical sprue (small intestine involvement, recent travel)