DMARDs Disease-modifying antirheumatic drugs

• Facts:
  1) Methotrexate (1st line, dihydrofolate reductase inhibitor)
  2) Hydroxychloroquine
  3) Sulfasalazine
  4) Etanercept
  5) Azathioprine
  6) Leflunomide
• Indications:
  Rheumatoid arthritis (initiate treatment as soon as diagnosis is made)
• Side Effects:
  Methotrexate
  Macrocytic anemia
  Alopecia
  Hepatotoxicity
  Interstitial lung disease
  
  Hydroxycholoroquine
  VIsual disturbances
  Hemolysis in G6PD
  GI distress