Glucagonoma

• Facts:
  Tumor of the islet cells of the pancreas
  
  Excess glucagon causes glucose intolerance, hyperglycemia and distinct skin lesions 'necrolytic migratory erythema'
• History / PE:
  Hyperglycemia, necrolytic migratory erythema, diarrhea
  Weight loss
  Anemia
• Diagnosis:
  Elevated levels of fasting glucose and glucagon
• Treatment:
  Surgical removal (tumor unresponsive to chemo)