Hyperandrogenism with virilization

• Diagnosis:
  Measurement of DHEAS and serum testosterone (helps delineate the site of excess androgen production)
  
  Ovarian source
  Elevated testosterone, with normal DHEAS levels
  
  Adrenal source
  Normal testosterone, with elevated DHEAS
• Notes:
  DHEA is secreted by both the ovaries and adrenal glands, but DHEAS (sulfated form) is specifically secreted by adrenals