McCune-Albright syndrome

McCune-Albright syndromeMcCune-Albright syndromeMcCune-Albright syndrome
  • Facts:
    Defect in the G-protein cAMP-kinase function
  • History / PE:
    Bone fractures
    Irregular, light brown "spots"
    Early puberty
  • Pneumonic:
    3 P's

    Precocious puberty
    Pigmentation (cafe au lait spots)
    Polyostotic fibrous dysplasia
  • See Also:
    Neurofibromatosis type 1
  • Associated With:
    Hyperthyroidism
    Adrenal hypercortisolism



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July 27th 2010