Migraine headaches

Migraine headaches
  • Facts:
    Affects females > males, with a usual onset in the 20s

    Triggers can include certain foods (eg. red wine), fasting, stress, OCPs, bright lights

    Thought to be caused by cortical spreading depression
  • History / PE:
    Nausea, vomiting
    Photophobia, phonophobia
    Unilateral, frontotemporal cephalgia
    Visual auras
  • Treatment:
    Avoid known triggers

    Abortive
    NSAIDs , ASA
    Sumatriptans
    Ergot alkaloids (ergotamine)
    Metoclopramide
    Chlorpromazine
    Prochlorperazine

    Prophylaxis
    Anticonvulsants (eg. depakote )
    Calcium channel blockers
    Beta blockers
    Tricyclic antidepressants
  • Complications:
    Status migrainosus (DHE protocol)
  • Associated With:
    Vascular and neurotransmitter (serotonin) changes



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August 4th 2010