Osteomalacia Vitamin D Deficiency

• Facts:
  Characterized by defective mineralization of bone, MC caused by vitamin D deficiency
  
  Seen in adults, after the closing of the epiphyseal growth plates
  
  Vitamin D deficiency leads to decreased intestinal calcium and phosphorus absorption
  
• History / PE:
  Muscle weakness
  Diffuse body pains
  Pseudofractures, blurring of the spine (radiological findings)
• Diagnosis:
  Low to low-normal serum calcium levels, hypophosphatemia
  Increased serum parathyroid hormone levels
• Treatment:
  Vitamin D supplementation
  Calcium
  Phosphate
  
• See Also:
  1) Rickets (defective mineralization of bone AND growth plate cartilage)
  2) Paget's disease (disordered skeletal remodeling)
  3) Osteoporosis (decreased bone mass)
• Associated With:
  RTA type II