Pheochromocytoma

• Facts:
  Tumor in adrenal medulla or in extra-adrenal site that secretes catecholamines
• History / PE:
  Excessive perspiration
  Uncontrolled HTN
  Tremors
  Abdominal pain
• Diagnosis:
  24hr metanephrines
  MIBG scan may help
• Treatment:
  Surgery
  Labetalol (has both alpha and beta blocking)
  
• Notes:
  Alpha blockade first, then beta blockers to control tachycardia
  Unopposed alpha blockade will lead to refractory HTN
  
  
• Associated With:
  vHL syndrome
  NF
  MEN IIa and MEN IIb
• Differential Diagnosis:
  Hyperthyroidism