DIRECT
(high potency, rapid inactivation by COMT, poor CNS penetration)
E pinephrine (α1, α, β1, β2)
N orepinephrine (α1, α2, β1)
I soproterenol (β1=β2)
D opamine ( low doses δ1 δ2, med doses β, high doses α )
DIRECT
(longer half lives, enter CNS)
P henylephrine (α1)
M ethoxamine (α1)
C lonidine (CNS, α2)
α methyldopa (CNS, α2)
D obutamine (β1>β2)
A lbuterol (β2)
T erbutaline (β2, inhibits premature labor)
INDIRECT
A mphetamine (narcolepsy, ADHD)
E phedrine
T urbutaline