Blastomycosis

• Facts:
  Pulmonary fungal infection endemic to Great Lakes, and Mississippi and Ohio River basins
  Usually affects lung, skin, bones/joints, and prostate
• History / PE:
  Low grade fevers, productive cough, weight loss
  Ulcerated skin lesions, lytic bone lesions (systemic disease)
• Diagnosis:
  Broad based budding yeast (sputum)
• Treatment:
  Itraconazole
  Amphotericin B
• Notes:
  Wisconsin has the highest infection rate
• Differential Diagnosis:
  Tuberculosis
  Histoplasmosis