1) At least two separate positive blood cultures for a typical organism
2) Persistent bacteria with any organism
3) Single positive culture of Coxiella burnetti
MINOR
1) Predisposing risk factors
2) Fever > 38.3 C
3) Vascular phenomena (septic emboli/infarcts, Janeway lesions )
4) Immunologic (Clomerulonephritis, Osler's nodes , Roth's spots )
5) Microbiological evidence that does not meet MAJOR cirteria
