Fluoroquinolones Quinolones

• Indications:
  Ciprofloxacin (Cipro)
  Pseudomonas (OE), UTI’s
  Poor G+
  
  Levofloxacin (Levaquin)
  Pneumonia , prostatitis, UTI, skin infections
  
  Moxifloxacin
  100x more active against Pneumococcus and G-
  More like Levo; kills some anaerobes
  Not useful for UTI’s; hepatically excreted; use for respiratory
  
  Norfloxacin(Noroxin)
• Side Effects:
  Tendon ruptures, especially in kids
  Neurotoxicity
• See Also:
  Antibiotics