Hashimoto's thyroiditis Chronic lymphocytic thyroiditis

• Facts:
  MCC of hypothyroidism
  Autoantibody destruction of thyroid follicles
• History / PE:
  Weight gain, hair loss
  Depression, fatigue
  Constipation
  
• Diagnosis:
  Anti-thyroperoxidase (TPO) antibodies
  Anti-thyroglobulin antibodies
  Increased TSH, decreased T4/T3
  High cholesterol
• Complications:
  Thyroid lymphoma (see rapid enlargement of the thyroid in patients with pre-existing Hashimoto's)
• Associated With:
  Non- hodgkin's lymphoma
• Differential Diagnosis:
  Secondary or tertiary hypothyroidism
  Thyroid hormone resistance (normal TSH, elevated T4/T3)