Loop diuretics

• Facts:
  Acts on the ascending loop of Henle by inhibiting Na+/K+/2Cl- transporter
  
  Drugs
  Furosemide (lasix)
  Ethacrynic acid
  Bumetanide
  Torsemide
  
  
• Pneumonic:
  Loop diuretics, Lose calcium
• Indications:
  Volume overload
  Ascites
• Side Effects:
  Metabolic acidosis
  Hypokalemia
  Hypocalcemia
  Ototoxicity
  SULFA allergy (except ethacrynic acid)
• See Also:
  Diuretic agents