MEN I Multiple Endocrine Neoplasia

• Facts:
  aka Wermer’s syndrome
  From mutations in menin (tumor suppressor) gene
• History / PE:
  Pancreatic islet tumors ( ZE syndrome, insulinomas, VIPomas)
  Parathyroid hyperplasia / adenomas
  Pituitary adenomas
• See Also:
  Multiple Endocrine Neoplasia