Porphyria cutanea tarda

Porphyria cutanea tardaPorphyria cutanea tarda
  • Facts:
    Deficiency of uroporphyrinogen decarboxylase (enzyme in heme synthesis)
    Triggered by certain substances (eg. ethanol, estrogrens)
  • History / PE:
    Painless blisters
    Facial hypertrichosis
    Increased skin fragility
    Hyperpigmentation
  • Diagnosis:
    Elevated porphyin levels
    Urine fluoresces orange-pink color (with Wood's lamp exam)
  • Treatment:
    Phlebotomy
    Hydroxychloroquine
  • Associated With:
    Hepatitis C



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August 3rd 2010