DiGeorge's syndrome Congenital thymic aplasia

• Facts:
  Caused by hypoplasia of the third and fourth pharyngeal pouches
  Microdeletion of 22q11
• History / PE:
  Hypocalcemia and tetany (from absent parathyroids) within 48hrs of birth
  Absent or hypoplastic thymus
  Congenital heart defects (cyanotic heart disease)
  Prolonged QT intervals (from hypocalcemia )
• Pneumonic:
  "CATCH 22 "
  
  C ardiac Abnormality (especially tetralogy of Fallot )
  A bnormal facies
  T hymic aplasia
  C left palate
  H ypocalcemia
  
  22 q11 microdeletion