Hypothyroidism

• Facts:
  Generalized resistance to thyroid hormones
• History / PE:
  Fatigue, cold intolerance
  Constipation , weight gain
  Diastolic HTN
  Hoarseness
  Myxedema
  Delayed relaxation of DTRs
• Treatment:
  Levothyroxine (synthroid)
• Complications:
  Myxedema coma (AMS, hypothermia)
  Hyperlipidemia (increased LDL) from decreased clearance due to decreased LDL receptors
• See Also:
  Thyroiditis
  Hyperthyroidism
• Associated With:
  Hashimoto's thyroiditis
  Amiodarone
  Carpal tunnel syndrome (accumulation of matrix substances)
  Chronic mucocutaneous candidiasis
• Differential Diagnosis:
  Sick euthyroid syndrome