Pemphigus vulgaris

• Facts:
  Blistering disease that affects skin and mucous membranes
• History / PE:
  Painful blisters
  Flaccid bullae
  Oral erosions and ulcerations
  Positive Nikolsky's sign
  
• Diagnosis:
  Intracellular IgG deposits in epidermis (on immunofluroescence)
  Autoantibodies against desmoglein
• Treatment:
  Azathioprine (immunosuppressive agent)
• Differential Diagnosis:
  Bullous pemphigoid (tense blisters, rarely oral lesions, IgG and C3)