Polycythemia vera

• History / PE:
  Hyperviscosity syndrome (easy bleeding/brusing, blurred vision, neurologic abnormalities, pruritis, hepatosplenomegaly, CHF)
• Diagnosis:
  Absence of measurable erythropoietin
  Hypertension
  High red cell mass
  Low ESR
  Thrombocytosis
• Treatment:
  Phlebotomy
  Hydroxyurea , interferon
  ASA (antithrombotic)
• Associated With:
  Secondary causes of polycythemia (hemoconcentration)
  
  1.) Excessive diureses
  2.) Severe gastroenteritis
  3.) Burns
• Differential Diagnosis:
  Hereditary telangiectasia