Porphyria cutanea tarda
Facts
:
Deficiency of uroporphyrinogen decarboxylase (enzyme in heme synthesis)
Triggered by certain substances (eg. ethanol, estrogrens)
History / PE
:
Painless blisters
Facial hypertrichosis
Increased skin fragility
Hyperpigmentation
Diagnosis
:
Elevated porphyin levels
Urine fluoresces
orange-pink color
(with Wood's lamp exam)
Treatment
:
Phlebotomy
Hydroxychloroquine
Associated With
:
Hepatitis
C
August 3rd 2010
Categories
Dermatology
Internal Medicine
Links
Files & Images
Painless hand blisters
Hypertrichosis