Hepatitis

• Facts:
  Inflammation of the liver leading to liver cell injury and necrosis
• Diagnosis:
  Increased ALT and AST
  Hepatitis serology
  Increased PT and serum transaminases
• Notes:
  ACUTE HEPATITIS
  
  1) Hepatitis A
  2) Hepatitis B
  3) Hepatitis C
  4) Hepatitis D
  5) Hepatitis E
  6) Drug induced (ETOH, INH, methyldopa, tylenol)
  
  CHRONIC HEPATITIS
  
  1) Hepatitis B
  2) Hepatitis C
  3) Hepatitis D
  4) Alcoholic hepatitis (mallory bodies)
  5) Autoimmune hepatitis
  6) Ischemic hepatitis
  7) WIlson's disease
  8) Hemochromatosis
  9) Alpha-1-antitrypsin deficiency
• See Also:
  PT is the single most important test to assess liver functioning, because all clotting factors (except for VIII) are synthesized in liver
  
  Serum transaminases signal leakage from injured hepatocytes