Premature ovarian failure

• Facts:
  Lack viable oocytes
  Commonly idiopathic
  
• History / PE:
  Women younger than 40 years old
  Amenorrhea
  Hypoestrogenism
  
• Diagnosis:
  Increased FSH/LH, decreased estrogen
• Treatment:
  Infertility (in vitro)
• Notes:
  FSH:LH ratio usually > 1.0 (takes longer for FSH to be cleared from circulation)
• See Also:
  Menopause
• Associated With:
  Hashimoto's thyroiditis
  Addison's disease
  Diabetes mellitus type 1
  Pernicious anemia
  H/O chemotherapy