Adenocarcinoma of tubular epithelial cells
80-90% of all malignant tumors of the kidney
Tumors can spread along renal vein to IVC
History / PE:
Hematuria, flank pain, palpable flank mass (classic triad)
Anemia
Polycythemia ( increased EPO )
Varicoceles that fail to empty in recumbent position (gonandal vein obstruction)
Diagnosis:
CT scan
Treatment:
Surgical resection
Sorafenib, sunitinib (new tyrosine kinase inhibitors)