Idiopathic thrombocytopenic purpura ITP

• Facts:
  MC immunologic disorder in women of childbearing age
  Common acquired bleeding disorder of childhood (post viral)
  IgG antibodies against platelets
• History / PE:
  Easy bruisabilty
  Petechiae
  Occasional epistaxis
• Diagnosis:
  Diagnosis of exclusion
  Thrombocytopenia
  Normal PT, pTT, Hb, WBC
  Positive CCOMBS' test
• Treatment:
  Patients with symptomatic bleeding (< 20,000)
  Corticosteroids
  IVIG
  Splenectomy
  Rituximab
• Notes:
  Platelet transfusions do NOT work
• See Also:
  Thrombotic thrombocytopenia purpura
  Hemolytic uremic syndrome
  Clotting disorders
• Associated With:
  Hepatitis C