Idiopathic thrombocytopenic purpura ITP

  • Facts:
    MC immunologic disorder in women of childbearing age
    Common acquired bleeding disorder of childhood (post viral)
    IgG antibodies against platelets
  • History / PE:
    Easy bruisabilty
    Petechiae
    Occasional epistaxis
  • Diagnosis:
    Diagnosis of exclusion
    Thrombocytopenia
    Normal PT, pTT, Hb, WBC
    Positive CCOMBS' test
  • Treatment:
    Patients with symptomatic bleeding (< 20,000)
    Corticosteroids
    IVIG
    Splenectomy
    Rituximab
  • Notes:
    Platelet transfusions do NOT work
  • See Also:
    Thrombotic thrombocytopenia purpura
    Hemolytic uremic syndrome
    Clotting disorders
  • Associated With:
    Hepatitis C



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August 2nd 2010