Membranous glomerulonephritis

  • Facts:
    Nephrotic syndrome
    MC nephropathy in Caucasian adults
  • Diagnosis:
    "Spike-and-dome " appearance due to granular deposits of IgG and C3 at the basement membrane
  • Treatment:
    Prednisone and cytotoxic therapy (severe disease)
  • Complications:
    Renal vein thrombosis ( antithrombin III is lost in the urine )
  • Associated With:
    1) Active hepatitis B (especially in children)
    2) Syphilis
    3) Malaria
    4) Gold

Review Edit Entry New Entry

August 5th 2010