Nephrotic syndrome Glomerulonephritis

• Facts:
  Proteinuria > 3.5g/day
  Approximately 1/3 of cases result from systemic disease (SLE, DM, amyloidosis )
• History / PE:
  Hypoalbuminemia
  Hyperlipidemia
  "Foamy" urine
  Generalized edema
• Diagnosis:
  1) Minimal change disease
  2) Focal segmental glomerulosclerosis
  3) Membranous glomerulonephritis (MC nephropathy)
  4) Diabetic nephropathy
  5) Lupus nephritis
  6) Renal amyloidosis
  7) Membranoproliferative nephropathy
• Treatment:
  ACEIs
  Protein and salt restriction
  PPV23 vaccination (for S. pneumoniae)
• Complications:
  Hypercoagulability ( renal vein thrombosis )
  Accelerated atherosclerosis
  Vitamin D deficiency
  Protein malnutrition
  Increased susceptibility to infections
• See Also:
  Nephritic syndrome