Nucleoside analog reverse transcriptase inhibitors NARTI or NRTI

  • Facts:
    First class of antiretroviral drugs developed
  • Notes:
    Zidovudine (AZT, trade name Retrovir)
    First HIV antiretroviral drug approved by the FDA

    Didanosine (ddI, trade name Videx)
    Second FDA-approved antiretroviral drug
    Analog of adenosine

    Stavudin (d4T, trade names Zerit)

    Lamivudine (3TC, trade name Epivir)
    Treatment of both HIV and hepatitis B

    Abacavir (ABC, trade name Ziagen)
    Analog of guanosine

    Emtricitabine (FTC, trade name Emtriva [formerly Coviracil] )
    Structurally similar to lamivudine
    Approved for the treatment of HIV, undergoing clinical trials for hepatitis B
  • See Also:
    Human Immunodeficiency Virus

Review Edit Entry New Entry

July 22nd 2010